Jeff S Coombes Selected Research

F2-Isoprostanes (F2 Isoprostanes)

12/2020	High day-to-day and diurnal variability of oxidative stress and inflammation biomarkers in people with type 2 diabetes mellitus and healthy individuals.
1/2020	Inspiratory flow-resistive breathing, respiratory muscle-induced systemic oxidative stress, and diaphragm fatigue in healthy humans.
10/2017	Exercise intensity, redox homeostasis and inflammation in type 2 diabetes mellitus.
2/2016	Synbiotics Easing Renal Failure by Improving Gut Microbiology (SYNERGY): A Randomized Trial.
1/2016	Astaxanthin has no effect on arterial stiffness, oxidative stress, or inflammation in renal transplant recipients: a randomized controlled trial (the XANTHIN trial).
12/2015	High intensity interval training favourably affects antioxidant and inflammation mRNA expression in early-stage chronic kidney disease.
5/2015	Oxidative stress contributes to muscle atrophy in chronic kidney disease patients.
3/2009	Comparison of markers of oxidative stress, inflammation and arterial stiffness between incident hemodialysis and peritoneal dialysis patients--an observational study.

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Jeff S Coombes Research Topics

Disease

28	Inflammation (Inflammations) 01/2022 - 06/2007
27	Cardiovascular Diseases (Cardiovascular Disease) 01/2021 - 12/2003
20	Chronic Renal Insufficiency 12/2018 - 07/2007
8	Insulin Resistance 01/2022 - 11/2008
8	Type 2 Diabetes Mellitus (MODY) 12/2020 - 11/2008
8	Atherosclerosis 12/2014 - 11/2002
7	Kidney Diseases (Kidney Disease) 01/2015 - 03/2008
6	Metabolic Syndrome (Dysmetabolic Syndrome X) 10/2020 - 08/2007
6	Obesity 01/2020 - 12/2014
5	Hypertension (High Blood Pressure) 01/2022 - 01/2010
5	Fatigue 01/2020 - 01/2003
5	Chronic Kidney Failure (Chronic Renal Failure) 12/2017 - 10/2008
5	Weight Loss (Weight Reduction) 10/2015 - 10/2008
4	Fibrosis (Cirrhosis) 01/2021 - 03/2011
4	Acute Kidney Injury (Acute Renal Failure) 01/2018 - 06/2009
4	Albuminuria 10/2017 - 07/2014
3	Necrosis 01/2022 - 03/2012
3	Hypertrophy 12/2021 - 09/2015
3	Proteinuria 02/2016 - 11/2010
2	Coronary Artery Disease (Coronary Atherosclerosis) 03/2022 - 01/2021
2	Ischemia 01/2018 - 12/2006
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2018 - 05/2012
2	Non-alcoholic Fatty Liver Disease 12/2017 - 12/2014
2	Renal Insufficiency (Renal Failure) 10/2015 - 07/2014
2	Myocardial Ischemia (Ischemic Heart Diseases) 05/2012 - 07/2009
2	Gilbert Disease 05/2012 - 08/2008
2	Dehydration (Water Stress) 05/2010 - 12/2009
1	Critical Illness (Critically Ill) 01/2022
1	Weight Gain 03/2021
1	Frailty 01/2021
1	Arterial Occlusive Diseases (Arterial Occlusive Disease) 01/2021
1	Epilepsy (Aura) 01/2021
1	Sarcopenia 01/2021
1	Prostatic Neoplasms (Prostate Cancer) 02/2020
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2020
1	Diabetes Mellitus 01/2020

Drug/Important Bio-Agent (IBA)

25	AntioxidantsIBA 12/2020 - 01/2003
16	Biomarkers (Surrogate Marker)IBA 12/2020 - 05/2010
8	Proteins (Proteins, Gene)FDA Link 12/2021 - 03/2008
8	F2-Isoprostanes (F2 Isoprostanes)IBA 12/2020 - 03/2009
6	LipidsIBA 01/2020 - 03/2008
6	CreatinineIBA 12/2018 - 03/2008
6	Atorvastatin (Lipitor)FDA Link 10/2015 - 03/2008
5	Glutathione PeroxidaseIBA 12/2020 - 07/2008
5	Uremic ToxinsIBA 02/2017 - 05/2014
5	astaxanthine (astaxanthin)IBA 01/2016 - 12/2008
5	CatalaseIBA 12/2015 - 07/2008
4	Oxygen (Dioxygen)IBA 01/2017 - 09/2014
4	EnzymesIBA 12/2015 - 07/2008
4	BilirubinIBA 10/2015 - 08/2008
4	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 10/2015 - 02/2010
3	Blood Glucose (Blood Sugar)IBA 01/2022 - 11/2008
3	Insulin (Novolin)FDA Link 01/2022 - 11/2008
3	Interleukin-6 (Interleukin 6)IBA 01/2022 - 06/2012
3	C-Reactive ProteinIBA 01/2022 - 06/2007
3	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 01/2012
3	CytokinesIBA 04/2019 - 06/2007
3	PTX3 proteinIBA 01/2016 - 12/2008
3	ApolipoproteinsIBA 01/2015 - 08/2013
3	Vitamin E FDA LinkGeneric 02/2012 - 04/2006
3	Superoxide DismutaseIBA 09/2011 - 01/2003
3	Thioctic Acid (Lipoic Acid)IBA 12/2006 - 09/2004
2	Ribosomal RNAIBA 12/2021 - 02/2016
2	Superoxide Dismutase-1IBA 01/2020 - 12/2015
2	Interleukin-22 (IL-22)IBA 01/2020 - 04/2019
2	Cystatin CIBA 12/2018 - 01/2012
2	AlbuminsIBA 10/2017 - 01/2015
2	Messenger RNA (mRNA)IBA 01/2017 - 12/2015
2	Phosphotransferases (Kinase)IBA 09/2015 - 08/2013
2	Urea (Carbamide)FDA LinkGeneric 01/2015 - 06/2009
2	Pharmaceutical PreparationsIBA 01/2015 - 03/2008
2	Triglycerides (Triacylglycerol)IBA 12/2014 - 11/2008
2	IsoprostanesIBA 03/2014 - 12/2008
2	Lipoproteins (Lipoprotein)IBA 05/2012 - 12/2004
2	Sulfhydryl Compounds (Thiols)IBA 05/2012 - 09/2004
2	oxidized low density lipoproteinIBA 05/2012 - 01/2006
2	Carotenoids (Carotene)IBA 02/2012 - 07/2009
2	Fish OilsIBA 09/2011 - 03/2011
2	Hydrocortisone (Cortisol)FDA LinkGeneric 05/2010 - 06/2007
2	LDL Lipoproteins (beta Lipoproteins)IBA 01/2006 - 11/2002
1	N(6)-carboxymethyllysine (carboxymethyllysine)IBA 01/2022
1	Receptor for Advanced Glycation End ProductsIBA 01/2022
1	Advanced Glycation End ProductsIBA 01/2022
1	Transcription Factors (Transcription Factor)IBA 12/2021
1	Clostridium perfringens epsilon-toxinIBA 01/2021
1	Amino Acids FDA Link 01/2020

Therapy/Procedure

10	Therapeutics 01/2021 - 11/2010
6	Liver Transplantation 03/2021 - 02/2012
5	Nephrectomy 01/2020 - 12/2014
4	Renal Dialysis (Hemodialysis) 01/2010 - 03/2005
3	Resistance Training 12/2021 - 02/2016
2	Cardiac Rehabilitation 03/2022 - 01/2021
2	Kidney Transplantation 06/2012 - 10/2008
2	Fluid Therapy (Oral Rehydration Therapy) 05/2010 - 12/2009
2	Bariatric Surgery 04/2010 - 10/2008
2	Peritoneal Dialysis 03/2009 - 08/2007
1	Aftercare (After-Treatment) 01/2022
1	Steam Bath (Sauna) 01/2021
1	Immunotherapy 02/2020
1	Drug Therapy (Chemotherapy) 02/2020